Talks & Discussions

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The purpose of these tables is to maintain a schedule of scientific talks and discussions relevant to your program.

Go to current week.⬇

Week 1
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon, July 21
 09:30
 Aud
 Boris, Paul, Maggie
 QBIO Course orientation

14:00
 Aud
 All participants
 superbugs organizational mtg

15:30
 SSR
 Students
 student presentations
Tue, 22
 09:30-11:30
 Aud
 Dan Andersson
 Tutorial: Basic Bacteriology

13:30
 SSR
 Students
 Programming/Microfluidics/Microbiology
Wed, 23
 09:30-11:00
 Aud
 Thomas Norman
 Stochasticity and cell fate choice in Bacillus subtilis

11:00-12:30
 Aud
 Bruce Levin


13:30
 SSR
 Students
 Programming/Microfluidics/Microbiology
Thu, 24
 09:30-10:30
 Aud
 Dan Weinreich
 Fitness Landscapes

10:30-11:30
 Aud
 Arjan de Visser
 Drug resistance landscapes

13:30
 SSR
 Students
 Programming/Microfluidics/Microbiology

14:00 - 15:30
 Aud
 program participants
 informal 5min talks by whoever wants
 NO RECORDING
Fri, 25
 09:30-11:00
 Aud
 Terry Hwa
 Bacterial metabolism

11:00-12:30
 Aud
 Erik v Nimwegen
 Bacterial genomics

13:30
 SSR
 Students
 Programming/Microfluidics/Microbiology

Week 2
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon, 28
 09:30-10:30
 Aud
 Nathalie Balaban
 Single-Cell Variability of Growth in Bacteria as an Optimization Process

10:45 - 11:45
 Aud
 Sanna Koskiniemi
 Contact-dependent growth inhibition in bacteria

12:15-13:30
 MSR
 Dan Weinreich
 Drug resistance evolution
 BLACKBOARD LUNCH

14:00
 Aud
 program participants
 Organisation
 NO RECORDING
Tue, 29
 09:30-10:50
 Aud
 Ulrich Nübel
 Genomic epidemiology of healthcare-associated bacterial pathogens

11:10 -- 12:30
 Aud
 Erik v Nimwegen
 Benefits of an erratic boss: Expression noise facilitates the evolution of gene regulation

16:00 -- 17:00
Gwenan Knight
 Determining the drivers of antibiotic resistance epidemiology
Wed, 30
 09:30-10:50
 Aud
 Daniel Fisher
 Evolutionary dynamics in large populations and high dimensions

11:10-12:30
 Aud
 Isabel Gordo
 Evolution of E coli within ecosystems

16:00
 SSR
 Ulrich, Richard et al
 Discussion about hospital acquired MRSA spread, diversity, and evolution
 NO RECORDING
Thu, 31
 09:30-10:50
 Aud
 Sasha Levy
 Quantitative evolutionary dynamics of one million barcoded lineages

11:10-12:30
 Aud
 Michael Mwangi
 Heterogeneous beta-lactam resistance: A little-known but potentially huge problem
Fri, 01
 09:30-11:00
 Aud
 David Weitz
 Drop-based microfluidics for single-cell studies


Week 3
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon, Aug 4
 09:30 -- 11:00
 Aud
 Dan Andersson
 Evolution of resistance at very low antibiotic levels
Tue, 5
 09:30 -- 10:50
 Aud
 Martin Weigt
 Residue coevolution in proteins - from 3D structure prediction to inferring mutational landscapes

16:00 -- 17:00
 SSR
 Tim Downing
 Escherichia coli ST131 genomes from long-term care facilities highlight subtype displacement and pervasive recombination
Wed, 6
 09:30 -- 10:50
 Aud
 Bonnie Bassler
 Small RNA Control of Quorum Sensing in Bacteria

11:10 -- 12:30
 Aud
 Ned Wingreen
 Modelling quorum sensing and 16S metagenomics of the human tongue
Thu, 7
 09:30 -- 10:50
 Aud
 Andrew Murray
 Rigorous Speculation? Engineering and Experiment on the Evolution of Novelty

16:00 -- 17:00
 SSR
 Klas Udekwu
 Stationary phase consideration of Staphylococcus aureus chemotherapy; pitfalls and whatnot
Fri
 09:30 -- 10:50
 Aud
 Paul Rainey
 Life cycles, fitness decoupling and the evolution of multicellularity

Week 4
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon, 11
 9:30 -- 10:50
 Aud
 Oskar Hallatschek
 Speed and patterns of evolutionary spreading
Tue,12
 09:30 -- 10:50
 Aud
 Michael Laub
 Specificity and Evolution of Bacterial Signaling Pathways

11:10 -- 12:30
 Aud
 Michael Elowitz
 Time-based regulation in individual cells

18:30
 SB
Screening of "Resistance" + panel discussion
 http://www.kitp.ucsb.edu/news/resistance
Wed,13
 09:30 -- 11:30
 Aud
 Richard Neher
Lloyd Ung
 Intra-patient HIV evolution
QBio course tutorial on (droplet) microfluidics chip design

16:00 -- 17:00
 SSR
 Anne-Florence Bitbol
 Quantifying the role of population subdivision in evolution on rugged fitness landscapes
Thu,14
 09:30 -- 10:50
 Aud
 Celia Schiffer
 Combating Drug Resistance: Lessons From Viruses: Influenza, HIV and HCV

16:00 -- 17:00
 SSR
 Mehran Kardar
 Predicting the evolution of drug resistance in HIV Protease
Fri. 15
 09:30 -- 10:50
 Aud
 Alan Perelson
 Modelling HCV infection, therapy and drug resistance

11:10 -- 12:30
 Aud
 Charlotte Hedskog
 Genotype and Subtype independent Full Genome Sequencing Assay for Hepatitis C Virus

16:00 -- 20:00
at Goleta Beach
 Barbeque

Week 5
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon, Aug 18
 09:30 -- 10:50
 Aud
 Alex Sigal
 Infection by the numbers: Effect of multiplicity of infection on infection outcome in HIV and TB

11:10 -- 12:30
 Aud
 Igor Rouzine
 An Evolutionary Role for HIV Latency in Enhancing Viral Transmission
Tue, 19
 09:30 -- 10:50
 Aud
 Colin Russell
 The global circulation of seasonal influenza viruses

11:10 -- 12:30
 Aud
 Katia Koelle
 The role of deleterious mutations in influenza's adaptive (antigenic) evolution
Wed, 20
 09:30 -- 10:50
 Aud
 Marta Luksza/Michael Laessig
 Predicting the evolution of human influenza

11:10 -- 12:30
 Aud
 Boris Shraiman/Richard Neher
 Predicting evolution from the shape of genealogical trees
Thu, 21
 09:30 -- 10:50
 Aud
 Roy Kishony
 Real-time evolution

11:10 -- 12:30
 Aud
 Paul Turner
 RNA virus adaptation (or not) to environmental change
Fri, 22
 10:30 -- 14:30
 Aud
 Student Presentations
Lunch break

16:00 -- ???
 Goleta Beach
 Barbecue



Week 6
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon Aug 25
 09:30 -- 10:50
 Aud
 Dominic Kwiatkowski
 Observing drug resistance as it emerges

11:10 -- 12:30
 Aud
 Philipp Messer
 Population genetics of selective sweeps in drug resistance evolution
Tue Aug 26
 09:30 -- 10:50
 Aud
 Ian Cheeseman
 Finding drug resistance genes

11:10 -- 12:30
 Aud
 Trevor Bedford
 Influenza antigenic evolution and vaccine strain selection
Wed Aug 27
 09:30 -- 10:50
 Aud
 Richard Maude
 Eliminating artemisinin-resistant malaria
Thu Aug 28
 09:30 -- 10:50
 Aud
 Roberto Amato
 Genetic architecture and evolution of artemisinin resistance in Plasmodium falciparum
Fri Aug 29
 09:30 -- 10:50
 Aud
 Alfred Ngwa
 Temporal changes in Plasmodium falciparum populations in the Gambia

Week 7
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon Sep 1



KITP closed. Labour Day
Tue Sep 2
 09:30 -- 10:50
 Aud
 Tim Downing
 Extensive and adaptive genome structure variation drives the evolution and epidemiology of visceral leishmaniasis in the Indian subcontinent
Wed Sep 3
 09:30 -- 10:50
 Aud
 Chris Illingworth
 Localising selection from resequencing data: Linking genes to phenotypes in malaria parasites

16:00 -- 16:30
 Ocean Room
 Program participants
 Journal club: Gire et al, "Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak", Science, published online 28 August 2014, DOI: 10.1126/science.1259657.
 Journal, paper and SI.
Thu Sep 4
 09:30 -- 10:50
 SSR
 Ville Mustonen
 The emergence of resistant clones in heterogeneous populations

16:00 -- 16:45
 Aud
 Michael Hochberg
 A window of opportunity to control the bacterial pathogen Pseudomonas aeruginosa combining antibiotics and phages
Fri Sep 5
 09:30--10:50
 Aud
 C. Brandon Ogbunu
 Fitness landscape by environment interactions inform models of rational drug therapy in P. falciparum

Week 8
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon Sept 8
 09:30 - 10:00
 Aud
 Ville Mustonen and Dan Weinreich
 What can theory do for human health?

10:15 - 12:00
 Aud
 Robert Gatenby
 TBD

16:00 - 17:00
 SSR
 Larry Nagahara
 TBD
Tue Sept 9
 09:30 - 10:50
 Aud
 Joel Brown
 Cancer therapy as an evolutionary game

11:10 - 12:30
 Aud
 Dan Weinreich
 Genomic clustering of driver mutations favors the evolution of chromosomal instability

15:30 - 17:00
 SSR
 Brown and Gatenby
 Data brainstorming
Wed Sept 10
 09:30 - 10:50
 Aud
 Michael Hochberg
 Long-term management of tumor growth and resistance
Thu Sept 11
 09:30 - 10:50
 Aud
 Chris Greenman
 Problems with modelling mutational and clonal features of epithelial tissues

11:10 - 12:30
 Aud
 Darryl Shibata
 Is it possible to reconstruct the first few divisions after human tumor initiation? (And why this might be important!)
Fri Sept 12
 09:30 - 10:50
 Aud
 Marco Gerlinger
 Genetic complexity of drug resistance evolution: implications for clinical predictions and therapy in GI and renal cancers

11:10 - 12:30
 Aud
 Joe Gray
 A spatial systems biology approach to therapeutic resistance in cancer

Template


Week 9
 Time
 Place*
 Speaker
 Title
 Comments, Links,...
Mon Sept 15
 9:30 - 10:50
 Aud
 Kristin Swanson
 Quantifying and Predicting Glioblastoma Dynamics: Untreated Growth, Response to Therapy and Recurrence Kinetics

11:10 - 12:30
 Aud
 Joshua Rubin
 Consequences of sexual selection on cancer rates and therapeutic responses
Tue, Sept 16
 9:30 - 10:50
 Aud
 Tom Mikkelsen
 TBD
 FIRE DRILL

11:10 - 12:30
 Aud
 Santosh Kesari
 Personalizing therapies for brain cancers
 THIS MORNING!

15:30 - 17:00
 SSR
Brain cancer data brainstorm
Wed
 9:30 - 11:30
 Aud
 Kim Grafton
 What is tumor board?

15:30 - 17:00
 Aud
 Milan Mikale
 Drug delivery challenges and tumor resistance
Thu
 9:30 - 10:50
 Aud
 Ben Raphael
 Genetic intratumor heterogeneity

11:10 - 12:30
 Aud
 Sohrab Shah
 Clonal dynamics in space and time in human cancer
Fri
 9:30 - 11:00
 Aud
 Dan, Ville and Bob
 What have we learned?

*Aud=Auditorium, SSR=Small Seminar Room, MSR=Main Seminar Room FR=Founders' Room
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